The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2022

Filed:

Jan. 23, 2019
Applicants:

Siemens Healthcare Gmbh, Erlangen, DE;

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Inventors:

Pascal Sati, Rockville, MD (US);

Sunil Goraksha Patil, Ellicott City, MD (US);

Daniel Reich, Washington, DC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/055 (2006.01); G06T 7/00 (2017.01); G01R 33/56 (2006.01); G01R 33/565 (2006.01); G06T 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0042 (2013.01); A61B 5/055 (2013.01); G01R 33/5608 (2013.01); G01R 33/56509 (2013.01); G06T 7/0012 (2013.01); G06T 5/00 (2013.01); G06T 2207/10088 (2013.01); G06T 2207/20024 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20172 (2013.01); G06T 2207/30016 (2013.01); G06T 2207/30096 (2013.01);
Abstract

A computer-implemented method for automatically identifying subjects at risk of Multiple Sclerosis (MS) includes acquiring a plurality of images of a subject's brain using a Magnetic Resonance Imaging (MRI) scanner. A contrast enhancement process is applied to each image to generate a plurality of contrast-enhanced images. An automated lesion detection algorithm is applied to detect one or more lesions present in the contrast-enhanced images. An automated central vein detection algorithm is applied to detect one or more central veins present in the contrast-enhanced images. An automated paramagnetic rim detection algorithm is applied to detect one or more paramagnetic rims present in the contrast-enhanced images. The patient's risk for MS may then be determined based on the one or more of the lesions, central veins, and paramagnetic rims present in the contrast-enhanced images.


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