The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Feb. 04, 2015
Gabriel P. Lopez, Durham, NC (US);
Ashutosh Chilkoti, Durham, NC (US);
Ali Ghoorchian, Durham, NC (US);
Felipe Garcia Quiroz, Durham, NC (US);
Duke University, Durham, NC (US);
Gabriel P. Lopez, Durham, NC (US);
Ashutosh Chilkoti, Durham, NC (US);
Ali Ghoorchian, Durham, NC (US);
Felipe Garcia Quiroz, Durham, NC (US);
Duke University, Durham, NC (US);
Abstract
The presently disclosed subject matter relates to modular peptide-substrate protease assays, in particular low cost and reliable methodology for measurement of protease and other enzyme activity that may be detected by optical turbidimetry or visual observation. The presently disclosed subject matter also relates to methods of using the disclosed assays within methods of detecting and monitoring diseases, methods of drug discovery, as well as in detection devices and systems.