The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Dec. 24, 2015
Applicants:

National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, JP;

Genedesign, Inc., Ibaraki, JP;

Inventors:

Ken Ishii, Ibaraki, JP;

Taiki Aoshi, Ibaraki, JP;

Hideaki Sato, Ibaraki, JP;

Attorney:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/117 (2010.01); A61K 9/127 (2006.01); A61K 31/7088 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C12N 15/117 (2013.01); A61K 9/127 (2013.01); A61K 31/7088 (2013.01); C12N 15/09 (2013.01); C12N 2310/17 (2013.01); C12N 2310/315 (2013.01);
Abstract

Provided are non-aggregating immunostimulatory oligonucleotides. The present invention also provides a delivery agent for an immunostimulatory-oligonucleotide nucleic acid medicine, said delivery agent including a nucleic acid that contains a phosphorothioated nucleotide. According to another aspect, the present invention further provides an oligonucleotide including a bioactive core, and a nucleic acid that contains a phosphorothioated nucleotide. The present invention yet further provides an immunostimulator including the bioactive core of a type A/D, type B/K, or type C immunostimulatory oligonucleotide.


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