The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Mar. 04, 2020
Applicant:
Rsem, Limited Partnership, Montreal, CA;
Inventor:
Przemyslaw Sapieha, Beaconsfield, CA;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12N 15/113 (2010.01); A61K 38/17 (2006.01); G01N 33/50 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); C07K 16/18 (2006.01); A61K 9/00 (2006.01); C12Q 1/6897 (2018.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01); A61K 35/30 (2015.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 9/0048 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 38/17 (2013.01); A61K 38/179 (2013.01); C07K 16/18 (2013.01); C12Q 1/6897 (2013.01); G01N 33/5023 (2013.01); G01N 33/6893 (2013.01); A61K 35/30 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2320/30 (2013.01); G01N 2333/705 (2013.01); G01N 2500/10 (2013.01); G01N 2800/164 (2013.01);
Abstract
Described herein is a method of preventing or treating ocular vascular hyperpermeability including macular edema, in a subject comprising inhibiting Sema3A activity. Also disclosed are compositions and their use for preventing or treating Sema3A-dependent ocular vascular hyperpermeability.