The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Jan. 31, 2017
Applicants:
Zhenglun Zhu, Newton, MA (US);
Hong Gao, Downingtown, PA (US);
Inventors:
Zhenglun Zhu, Newton, MA (US);
Hong Gao, Downingtown, PA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6883 (2018.01); A61K 31/7115 (2006.01); A61K 35/17 (2015.01); C12N 5/0786 (2010.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/7115 (2013.01); A61K 35/17 (2013.01); C12N 5/0645 (2013.01); C12N 15/113 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6883 (2013.01); G01N 33/5023 (2013.01); G01N 33/6875 (2013.01); A61P 29/00 (2018.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3233 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/4703 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7095 (2013.01);
Abstract
A method of treating an inflammatory disorder in a subject, comprising administering to the subject in need thereof a nucleic acid molecule for inhibiting the expression of Hom-1. Specifically, the nucleic acid molecule is an RNAi agent or an antisense morpholino oligonucleotide. Further disclosed is a method of selecting a therapeutic for an inflammatory disorder in a subject, or monitoring the efficacy of a therapeutic for an inflammatory disorder in a subject, comprising detecting the expression level of Hom-1 in an inflamed tissue sample obtained from the subject.