The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Mar. 04, 2015
Applicant:
Fate Therapeutics, Inc., San Diego, CA (US);
Inventors:
Bahram Valamehr, San Diego, CA (US);
Peter Flynn, San Diego, CA (US);
Ramzey Abujarour, San Diego, CA (US);
Megan Robinson, San Diego, CA (US);
Assignee:
FATE THERAPEUTICS, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01); C12N 5/073 (2010.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 5/0603 (2013.01); C12N 15/86 (2013.01); C12N 2501/115 (2013.01); C12N 2501/15 (2013.01); C12N 2501/235 (2013.01); C12N 2501/415 (2013.01); C12N 2501/724 (2013.01); C12N 2501/727 (2013.01); C12N 2740/15043 (2013.01);
Abstract
The invention provides compositions and methods for manufacturing pluripotent cells. In particular, the invention provides improved culture platforms for manufacturing pluripotent cells with ground state pluripotency. In various embodiments, the invention contemplates, in part, a composition comprising: (a) a Wnt pathway agonist; (b) a MEK inhibitor; and (c) a ROCK inhibitor. In certain embodiments, the composition further comprises bFGF or LIF.