The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Oct. 09, 2018
Applicants:
Daiichi Sankyo Europe Gmbh, Munich, DE;
Amgen Inc, Thousand Oaks, CA (US);
Inventors:
Mike Rothe, Krailling, DE;
Martin Treder, Reilingen, DE;
Eric Borges, Biberach, DE;
Larry L. Green, Pasadena, CA (US);
Susanne Hartmann, Munich, DE;
Assignees:
Daiichi Sankyo Europe GmbH, Munich, DE;
Amgen Inc., Thousand Oaks, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/32 (2006.01); G01N 33/574 (2006.01); C12N 15/00 (2006.01); C12N 15/63 (2006.01); C12N 15/09 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); C07K 16/2863 (2013.01); G01N 33/574 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C12N 15/00 (2013.01); C12N 15/09 (2013.01); C12N 15/63 (2013.01); C12N 2800/00 (2013.01);
Abstract
The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.