The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Jan. 28, 2015
Applicant:
Sanofi, Paris, FR;
Inventors:
Assignee:
SANOFI, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/46 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2839 (2013.01); C07K 16/2842 (2013.01); C07K 2317/24 (2013.01); C07K 2317/52 (2013.01); C07K 2317/524 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01);
Abstract
The invention relates to antibodies directed to α2β1 integrin and their uses, including humanized anti-alpha 2 (α2) integrin antibodies and methods of treatment with anti-α2 integrin antibodies. More specifically the present invention relates to humanized anti-α2 integrin antibodies comprising a heavy chain variable region, a light chain variable region, a human light chain constant region and a variant human IgG1 heavy chain constant region which exhibit altered effector function.