The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Feb. 13, 2018
Applicants:

Shanghai Junshi Biosciences Co., Ltd., Shanghai, CN;

Suzhou Junmeng Biosciences Co., Ltd., Jiangsu, CN;

Inventors:

Hai Wu, Shanghai, CN;

Sheng Yao, Shanghai, CN;

Yuehua Zhou, Jiangsu, CN;

Jian Yao, Shanghai, CN;

Dan Meng, Jiangsu, CN;

Hui Feng, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/46 (2006.01); C07H 21/04 (2006.01); C12P 21/06 (2006.01); C12N 1/20 (2006.01); C12N 15/74 (2006.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61P 35/00 (2018.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01);
Abstract

An antibody or a functional fragment thereof that specifically bind to PD-L1 with high affinity, a nucleic acid molecule that encodes said antibody or the functional fragment thereof, an expression vector and a host cell for use in expressing said antibody or the functional fragment thereof, and a method for producing said antibody or the functional fragment thereof. An immunoconjugate and a pharmaceutical composition containing said antibody or the functional fragment thereof, and a method for using said antibody or the functional fragment thereof to enhance the function of a T cell so as to up-regulate a cell-mediated immune response, for use in treating diseases caused by T cell dysfunction.


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