The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Apr. 24, 2020
Agenus Inc., Lexington, MA (US);
Ludwig Institute for Cancer Research Ltd, Zurich, CH;
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Marc Van Dijk, Bosch en Duin, NL;
Cornelia Anne Mundt, Lörrach, DE;
Gerd Ritter, New York, NY (US);
David Schaer, Mamaroneck, NY (US);
Jedd David Wolchok, New York, NY (US);
Taha Merghoub, Jersey City, NJ (US);
David Adam Savitsky, Boxford, MA (US);
Nicholas Stuart Wilson, San Carlos, CA (US);
Agenus Inc., Lexington, MA (US);
Ludwig Institute for Cancer Research Ltd., Zurich, CH;
Memorial Sloan-Kettering Cancer Center, New York, NY (US);
Abstract
The instant disclosure provides antibodies that specifically bind to human CTLA-4 and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.