The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Mar. 24, 2017
Applicant:

Eli Lilly and Company, Indianapolis, IN (US);

Inventors:

Stuart Willis Bright, Carmel, IN (US);

Julian Davies, La Jolla, CA (US);

Andrea Paula Martin, Carmel, IN (US);

Joshua Dade Poorbaugh, New Palestine, IN (US);

Oliver Schroeder, San Diego, CA (US);

Karen Leigh Cox, Martinsville, IN (US);

Angus John MacDonald, Indianapolis, IN (US);

Xiao-Fen Wang, San Diego, CA (US);

Sean Edward Sissons, Bargersville, IN (US);

Assignee:

ELI LILLY AND COMPANY, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07K 16/24 (2006.01); A61P 37/06 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); A61P 37/06 (2018.01); G01N 33/6869 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/92 (2013.01); G01N 2333/54 (2013.01); G01N 2800/101 (2013.01); G01N 2800/104 (2013.01);
Abstract

Provided are antibodies, or an antigen-binding fragment thereof, that binds human IL-21, These antibodies are useful in immunoassays of IL-21 levels, and/or in vivo, ex vivo or in vitro immunochemical and other imaging methods for determining the presence of IL-21 and/or quantifying IL-21 levels, and for diagnostic, prognostic and predictive purpose, and or optimizing therapeutic regimens in patients in which IL-21 signaling is implicated in pathogenesis.


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