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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11267872 B1

PDFFull Text
Date of Patent:
Mar. 08, 2022

Filed:

Apr. 16, 2019

Polyclonal antibodies produced using hiv-1 trimeric envelope glycoprotein subunits

Applicant:

Gnvie Llc, San Francisco, CA (US);

Inventors:

M. Scott Killian, San Francisco, CA (US);

Evelin Szakal, San Francisco, CA (US);

Girish N. Vyas, San Francisco, CA (US);

Assignee:

GNVIE LLC, San Francisco, CA (US);

Attorneys:

Shweta Chandra

Bozicevic, Field & Francis LLP

Primary Examiner:

Nicole Kinsey White

Int. Cl.
CPC ...
C07K 16/10 (2006.01); C07K 16/00 (2006.01); C07K 14/16 (2006.01); A61K 39/12 (2006.01); A61K 39/21 (2006.01); C12N 7/00 (2006.01); G01N 33/569 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1063 (2013.01); A61K 39/12 (2013.01); A61K 39/21 (2013.01); C07K 14/005 (2013.01); C07K 14/16 (2013.01); C07K 16/005 (2013.01); C12N 7/00 (2013.01); G01N 33/56983 (2013.01); G01N 33/56988 (2013.01); A61K 2039/5258 (2013.01); C07K 2317/10 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C12N 2740/16051 (2013.01); C12N 2740/16063 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01); C12N 2740/16171 (2013.01);
Abstract

Polyclonal Antibodies produced using HIV-1 Trimeric Envelope Glycoprotein Subunits (TEGS) are provided. TEGS are comprised of non-infectious complexes comprising a trimeric envelope glycoprotein subunit comprising gp120 bound to membrane-anchored trimeric native gp41. The gp120 and gp41 present in the TEGS are not chemically fixed or cross-linked. Immunization with the TEGS elicits polyclonal antibodies that neutralize diverse viruses in HIV infection assay using peripheral blood mononuclear cells (PBMCs). The present invention relates to a method for reducing the occurrence and/or severity of HIV infections.

Find Patent Forward Citations

Killian, M.. (2022). Polyclonal antibodies produced using hiv-1 trimeric envelope glycoprotein subunits (U.S. Patent No. 11267872). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11267872

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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