The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Jan. 28, 2020
Applicants:
University of Rhode Island Board of Trustees, Kingston, RI (US);
Yale University, New Haven, CT (US);
Inventors:
Yana K. Reshetnyak, Saunderstown, RI (US);
Oleg A. Andreev, Saunderstown, RI (US);
Anna Moshnikova, Warwick, RI (US);
Donald M. Engelman, New Haven, CT (US);
Assignees:
University of Rhode Island Board of Trustees, Kingston, RI (US);
Yale University, New Haven, CT (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/47 (2006.01); A61K 47/65 (2017.01); A61K 9/00 (2006.01); A61P 35/00 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C07K 14/4725 (2013.01); A61K 9/0019 (2013.01); A61K 47/646 (2017.08); A61K 47/65 (2017.08); A61P 35/00 (2018.01);
Abstract
The invention features a compositions and methods for inducing an immune response to targeted cells. The compositions induce targeting of a cell by positioning carbohydrate epitopes on the surface of the cell by conjugation of the epitope to a pH-triggered membrane peptide (pHLIP®).