The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Jun. 09, 2016
Applicant:
Firmenich SA, Satigny, CH;
Inventors:
Hyo-Young Jeong, Woodside, NY (US);
Patrick Pfister, Brooklyn, NY (US);
Matthew Rogers, Briarcliff Manor, NY (US);
Assignee:
FIRMENICH SA, Geneva, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C07K 14/47 (2006.01); C12N 5/10 (2006.01); C12N 15/85 (2006.01); C07K 14/705 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4705 (2013.01); C07K 14/47 (2013.01); C07K 14/705 (2013.01); C12N 5/10 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); G01N 33/502 (2013.01); C12N 2310/20 (2017.05); C12N 2510/02 (2013.01); C12N 2800/80 (2013.01); C12N 2830/00 (2013.01); G01N 2333/705 (2013.01); G01N 2500/10 (2013.01);
Abstract
Provided herein is a cell line with improved odorant receptor function comprising an activated endogenous RTP1 gene, which further expresses an RTP1 protein. Further provided herein is a method for specifically activating an endogenous RTP1 gene in a eukaryotic cell using a CRISPR/Cas9 derived technique. Also provided herein is a method for identifying compounds with desired effects such as perfume or aroma modulators in said cell line.