The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Nov. 17, 2017
Applicant:

Arcus Biosciences, Inc., Hayward, CA (US);

Inventors:

Jaroslaw Kalisiak, Mountain View, CA (US);

Kenneth V. Lawson, San Francisco, CA (US);

Manmohan Reddy Leleti, Dublin, CA (US);

Erick Allen Lindsey, Fremont, CA (US);

Dillon Harding Miles, Berkeley, CA (US);

Eric Newcomb, Menlo Park, CA (US);

Jay Patrick Powers, Pacifica, CA (US);

Ehesan Ul Sharif, Menlo Park, CA (US);

Assignee:

ARCUS BIOSCIENCES, INC., Hayward, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/23 (2006.01); C07H 19/16 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07H 19/23 (2013.01); C07H 19/16 (2013.01); A61K 45/06 (2013.01);
Abstract

Compounds that modulate the conversion of AMP to adenosine by 5'-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5′-nucleotidase, ecto is also provided.


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