The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Aug. 31, 2018
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Abdellah Tahri, Anderlecht, BE;

Jean-François Bonfanti, Andé, FR;

Tim Hugo Maria Jonckers, Heist-op-den-Berg, BE;

Pierre Jean-Marie Bernard Raboisson, Rosieres, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/06 (2006.01); C07H 19/10 (2006.01); C07H 19/16 (2006.01); C07H 19/20 (2006.01); A61P 31/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07H 19/20 (2013.01); A61K 45/06 (2013.01); A61P 31/14 (2018.01); C07H 19/06 (2013.01); C07H 19/10 (2013.01); C07H 19/16 (2013.01);
Abstract

The present invention relates to 2'-spirothietane nucleosides, and the phosphates and the prodrugs thereof, and the pharmaceutically acceptable salts and solvates thereof, and the use of such compounds as a medicament, in particular in the prevention and/or treatment of viral infections caused by viruses belonging to the Flaviviridae family and/or to the alphavirus genus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, and to the compositions or preparations for use as a medicament, more preferably for the prevention or treatment of viral infections caused by viruses belonging to the Flaviviridae family and/or to the alphavirus genus. The invention also relates to processes for the preparation of the compounds.


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