The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Aug. 21, 2018
Applicant:
Shenzhen Targetrx, Inc., Guangdong, CN;
Inventors:
Yihan Wang, Guangdong, CN;
Huanyin Li, Guangdong, CN;
Assignee:
Shenzhen TargetRx, Inc., Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61P 35/00 (2006.01); A61P 3/00 (2006.01); A61P 9/00 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/02 (2006.01); A61P 37/06 (2006.01); A61P 11/00 (2006.01); A61P 11/02 (2006.01); A61P 11/06 (2006.01); A61P 11/08 (2006.01); A61P 19/02 (2006.01); A61P 19/06 (2006.01); A61P 37/00 (2006.01); C07B 59/00 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61P 35/00 (2018.01);
Abstract
Provided are an aminopyrimidine compound as shown in formula (I), a polymorph, a pharmaceutically acceptable salt, a prodrug, a stereoisomer, an isotopic variant, a hydrate or a solvate thereof, and a pharmaceutical composition containing the same and the use thereof. The aminopyrimidine compound and the composition containing the same have excellent inhibition to protein kinases, and at the same time have better pharmacokinetic parameter characteristics, and can improve the drug concentration of the compound in animals, and thereby improve the efficacy and safety of the drug.