The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Mar. 21, 2020
Applicants:

San Diego State University Research Foundation, San Diego, CA (US);

Carewear Corp., Reno, NV (US);

Inventors:

Chukuka S. Enwemeka, San Diego, CA (US);

John C. Castel, Reno, NV (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 2/24 (2006.01); A61N 5/06 (2006.01); A61L 2/28 (2006.01); A61L 2/00 (2006.01); A61K 41/00 (2020.01); A61M 16/06 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61N 5/0624 (2013.01); A61K 41/0057 (2013.01); A61K 41/0061 (2013.01); A61K 41/0071 (2013.01); A61L 2/0052 (2013.01); A61L 2/0076 (2013.01); A61L 2/24 (2013.01); A61L 2/28 (2013.01); A61N 5/062 (2013.01); A61B 2017/00154 (2013.01); A61L 2202/11 (2013.01); A61M 16/06 (2013.01); A61M 2205/051 (2013.01); A61N 2005/0606 (2013.01); A61N 2005/0607 (2013.01); A61N 2005/0645 (2013.01); A61N 2005/0652 (2013.01); A61N 2005/0663 (2013.01);
Abstract

The present invention is directed to a system and method for photoeradication of microorganisms from a target. The method includes the step of obtaining test data for a plurality of experiments each of which comprises irradiating test microorganisms with a plurality of light pulses having a wavelength that ranges from 380 nm to 500 nm. The light pulses have a plurality of pulse parameters (peak irradiance, pulse duration, and off time between adjacent light pulses) and are provided at a radiant exposure that ranges from 0.5 J/cmto 60 J/cmduring each of a plurality of irradiation sessions. The test data comprises a survival rate for the test microorganisms after irradiation with the light pulses. The method also includes the step of analyzing the test data to identify the pulse parameters for the light pulses and the radiant exposure for each of the irradiation sessions that result in a desired survival rate for the test microorganisms. The method further includes the step of irradiating the microorganisms of the target with light pulses having the identified pulse parameters at the identified radiant exposure for each of the irradiation sessions so as to photoeradicate all or a portion of the microorganisms.


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