The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Dec. 09, 2014
Applicant:

Exthera Medical Corporation, Berkeley, CA (US);

Inventors:

Keith McCrea, Concord, CA (US);

Robert Ward, Orinda, CA (US);

Olle Larm, Bromma, SE;

Assignee:

ExThera Medical Corporation, Martinez, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/727 (2006.01); A61M 1/34 (2006.01); A61M 1/36 (2006.01);
U.S. Cl.
CPC ...
A61M 1/34 (2013.01); A61K 31/727 (2013.01); A61M 1/3679 (2013.01); A61M 2202/0478 (2013.01); A61M 2202/07 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/7545 (2013.01);
Abstract

The method is described as the removal of mediators that contribute to the pathogenesis of cancer from blood by contacting the blood with a solid, essentially non-micro-porous substrate which has been surface treated with heparin, heparan sulfate and, optionally, other molecules or chemical groups (the adsorbent media or media) having a binding affinity to the mediator, and wherein the size of the interstitial channels within said substrate are balanced with the amount of interstitial substrate surface area such that high flow rates of blood past said substrate creates a flow transport that is characterized by convection transport more than Brownian diffusion transport.


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