The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Nov. 26, 2014
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Mark Grinstaff, Brookline, MA (US);
Jonah Andrew Kaplan, Newton, MA (US);
Julia Wang, Forest Hills, NY (US);
Assignee:
TRUSTEES OF BOSTON UNIVERSITY, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/26 (2006.01); A61L 31/14 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 29/08 (2006.01); A61L 29/14 (2006.01); A61L 29/16 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01); A61K 9/51 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
A61L 31/14 (2013.01); A61K 9/5031 (2013.01); A61K 9/5146 (2013.01); A61L 27/34 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 29/085 (2013.01); A61L 29/14 (2013.01); A61L 29/16 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61L 2400/00 (2013.01);
Abstract
The disclosure provides a drug delivery device that can release a drug or other molecule of interest in response to application of a mechanical force, such as tension, and methods of use thereof. The present disclosure provides a tension-responsive drug delivery device by exploiting a difference in mechanical properties between a drug-loaded core material and a supertiydrophobic barrier coating consisting of interconnected micro- and nano-sized particles formulated via the electrospraying of a mixture of biocompatible polymers.