The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Jul. 27, 2017
Applicants:
The Fourth Military Medical University, Shaanxi, CN;
Shanghai Genbase Biotech Co., Ltd., Shanghai, CN;
Inventors:
Daiming Fan, Shaanxi, CN;
Yongzhan Nie, Shaanxi, CN;
Kaichun Wu, Shaanxi, CN;
Yueqiong Cao, Shanghai, CN;
Jijun Yuan, Shanghai, CN;
Xuejun Yu, Shanghai, CN;
Assignees:
THE FOURTH MILITARY MEDICAL UNIVERSITY XI'AN, Shaanxi, CN;
SHANGHAI GENBASE BIOTECH CO., LTD., Shanghai, CN;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61P 35/00 (2006.01); C07K 19/00 (2006.01); A61K 35/17 (2015.01); C12N 15/62 (2006.01); G01N 33/574 (2006.01); C12N 5/10 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 16/30 (2013.01); C07K 16/40 (2013.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 15/62 (2013.01); G01N 33/574 (2013.01);
Abstract
The present invention provides a glycosylated CEA-specific single-chain antibody, and a chimeric antigen receptor (CAR) targeting a glycosylated CEA, which can be used in manufacture of an agent or a medicament for diagnosis or treatment of a tumor overexpressing glycosylated CEA.