The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Dec. 29, 2017
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
Samuel Rahbar, Beverly Hills, CA (US);
Timothy W. Synold, Monrovia, CA (US);
John Termini, Altadena, CA (US);
Daniel Tamae, Duarte, CA (US);
Gerald Wuenschell, Duarte, CA (US);
Assignee:
CITY OF HOPE, Duarte, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/195 (2006.01); G01N 30/72 (2006.01); G01N 30/04 (2006.01); G01N 30/88 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/195 (2013.01); G01N 30/7233 (2013.01); G01N 30/7266 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); G01N 2030/045 (2013.01); G01N 2030/8827 (2013.01); G01N 2030/8868 (2013.01); G01N 2800/042 (2013.01);
Abstract
Methods of quantifying N-carboxyethyl-2'-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of disorders, including diabetes and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG levels before and after treatment. Measurement of CEdG levels occurs using liquid chromatography electrospray ionization tandem mass spectrometry.