The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
Feb. 08, 2017
Applicant:
Brandeis University, Waltham, MA (US);
Inventors:
Dorothee Kern, Waltham, MA (US);
Adelajda Zorba, Waltham, MA (US);
Assignee:
BRANDEIS UNIVERSITY, Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/395 (2006.01); A61K 31/192 (2006.01); A61K 45/06 (2006.01); A61K 31/496 (2006.01); A61K 31/517 (2006.01); C07K 16/40 (2006.01); C12Q 1/48 (2006.01); G16B 15/30 (2019.01); A61P 35/00 (2006.01); G16B 15/00 (2019.01); A61K 9/00 (2006.01); G16C 20/50 (2019.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 9/0019 (2013.01); A61K 31/496 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/40 (2013.01); C12Q 1/485 (2013.01); G16B 15/00 (2019.02); G16B 15/30 (2019.02); G01N 2500/04 (2013.01); G16C 20/50 (2019.02);
Abstract
The present invention features therapeutic compositions comprising an agent that specifically binds to a PIF pocket of Aurora A kinase and an agent that specifically binds to an ATP-binding site of Aurora A kinase, and the use of the therapeutic compositions to modulate Aurora A kinase for the treatment of cancer.