The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2022
Filed:
May. 15, 2017
Infectious Disease Research Institute, Seattle, WA (US);
University of Virginia Patent Foundation, Charlottesville, VA (US);
Christopher B. Fox, Sumner, WA (US);
Susan S. Lin, Seattle, WA (US);
Darrick Carter, Seattle, WA (US);
Neal Van Hoeven, Seattle, WA (US);
Mayuresh M. Abhyankar, Charlottesville, VA (US);
William A. Petri, Charlottesville, VA (US);
INFECTIOUS DISEASE RESEARCH INSTITUTE, Seattle, WA (US);
Abstract
Provided herein are PEGylated liposomes, and methods of making and using thereof. The PEGylated liposomes comprise at least a cholesterol, a non-PEGylated neutral lipid, and a PEGylated lipid, wherein the average molecular weight of the PEG component in the PEGylated lipid is about 5000 Daltons or less. The PEGylated liposomes are stable and capable of delivery of an agent for the generation of an immune response, for example an agent for vaccine, therapeutic, or diagnostic uses. Compositions and methods related to making the PEGylated liposomes and using the PEGylated liposomes for stimulating an immune response are also provided.