The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2022

Filed:

Jun. 08, 2018
Applicant:

William Tyler, Newton, MA (US);

Inventor:

William Tyler, Newton, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61B 8/08 (2006.01); A61B 5/00 (2006.01); G01R 33/48 (2006.01); G01R 33/563 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0042 (2013.01); A61B 5/0035 (2013.01); A61B 5/055 (2013.01); A61B 8/0808 (2013.01); A61B 8/485 (2013.01); A61B 8/5261 (2013.01); G01R 33/4814 (2013.01); G01R 33/56358 (2013.01);
Abstract

Methods, systems, and devices for mechanically disturbing tissues of the central nervous system including a brain of a subject are provided. An elastogram of brain tissue may be generated using mesoscopic wavelength ultrasound composed of longitudinal waves in brain tissues to produce micromechanical disturbances of brain nuclei and circuits for characterization of their mechanical properties (e.g., stiffness, elasticity, rigidity, viscoelasticity). A magnetic resonance elastography (MRE) system includes an MRE engine in electronic communication with at least one transducer and with a magnetic resonance imaging (MRI) device. The MRE engine is configured to electronically control operation of the at least one transducer to emit ultrasound, to electronically receive, from the MRI device, at least one signal indicative of measurements of displacement of the brain tissue by the ultrasound, and to electronically generate an elastogram of the brain tissue based on the at least one signal.


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