The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2022
Filed:
Apr. 06, 2017
Technion Research & Development Foundation Limited, Haifa, IL;
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Shai S. Shen-Orr, Karkur, IL;
Elina Starovetsky, Yokneam Ilit, IL;
Naama Maimon, Nir-Etzion, IL;
Purvesh Khatri, Menlo Park, CA (US);
Renaud Gaujoux, Cape Town, ZA;
Francesco Vallania, San Fransisco, CA (US);
Technion Research & Development Foundation Limited, Haifa, IL;
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Abstract
Provided are methods of predicting responsiveness of a subject having an inflammatory bowel disease (IBD) to a tumor necrosis factor (TNF)-alpha inhibitor, by analyzing a frequency of at least one subpopulation of immune cells in a tissue biopsy of the subject. Also provided are methods of selecting a treatment for a subject and kits for determining responsiveness of the subject to treatment with a TNF-alpha inhibitor.