The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2022
Filed:
May. 12, 2017
Applicant:
Ajou University Industry-academic Cooperation Foundation, Suwon-si, KR;
Inventors:
Tae Hwan Shin, Daegu, KR;
Geetika Phukan, Suwon-si, KR;
Man Jeong Paik, Seoul, KR;
Hyeon-Seong Lee, Incheon, KR;
Hyung-Jin Park, Suwon-si, KR;
Da Yeon Lee, Ulsan, KR;
Gwang Lee, Suwon-si, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6837 (2018.01); C12Q 1/6881 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/142 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01);
Abstract
A method of assessing neurotoxicity of nanoparticles, includes: preparing a tissue or cell sample of mammal exposed to the nanoparticles; analyzing at least one polyamine metabolite selected from the group consisting of putrescine, N1-acetylspermidine, N8-acetylspermidine, N1-acetylspermine and spermine in the sample; and comparing expression degree of the polyamine metabolite with that of a control.