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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11261475 B1

PDFFull Text
Date of Patent:
Mar. 01, 2022

Filed:

May. 12, 2017

Nano-neurotoxicity bio-marker composition based on intracellular aggregates which are biomarkers of degenerative brain diseases

Applicant:

Ajou University Industry-academic Cooperation Foundation, Suwon-si, KR;

Inventors:

Tae Hwan Shin, Daegu, KR;

Geetika Phukan, Suwon-si, KR;

Man Jeong Paik, Seoul, KR;

Hyeon-Seong Lee, Incheon, KR;

Hyung-Jin Park, Suwon-si, KR;

Da Yeon Lee, Ulsan, KR;

Gwang Lee, Suwon-si, KR;

Assignee:

AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;

Attorney:

Revolution IP, PLLC

Primary Examiner:

Robert T Crow

Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6837 (2018.01); C12Q 1/6881 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/142 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01);
Abstract

A method of assessing neurotoxicity of nanoparticles, includes: preparing a tissue or cell sample of mammal exposed to the nanoparticles; analyzing at least one polyamine metabolite selected from the group consisting of putrescine, N1-acetylspermidine, N8-acetylspermidine, N1-acetylspermine and spermine in the sample; and comparing expression degree of the polyamine metabolite with that of a control.

Find Patent Forward Citations

Shin, Tae. (2022). Nano-neurotoxicity bio-marker composition based on intracellular aggregates which are biomarkers of degenerative brain diseases (U.S. Patent No. 11261475). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11261475

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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