The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2022

Filed:

Jun. 28, 2020
Applicants:

Tel Hashomer Medical Research Infrastructure and Services Ltd., Ramat Gan, IL;

Ramot AT Tel Aviv University Ltd., Tel Aviv, IL;

Inventors:

Genady Kostenich, Ramat Gan, IL;

Mor Oron-Herman, Ramat Efal, IL;

Arie Orenstein, Tel Aviv, IL;

Talia Shekhter Zahavi, Petah-Tikva, IL;

Ehud Gazit, Ramat Hasharon, IL;

Yoseph Salitra, Rehovot, IL;

Ludmila Buzhansky, Ariel, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/655 (2006.01); A61K 38/08 (2019.01); A61K 38/12 (2006.01); A61K 47/62 (2017.01); A61K 47/69 (2017.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/655 (2013.01); A61K 38/08 (2013.01); A61K 38/12 (2013.01); A61K 47/62 (2017.08); A61K 47/6923 (2017.08); A61K 47/6933 (2017.08); A61K 47/6937 (2017.08); A61K 49/0043 (2013.01); A61K 49/0056 (2013.01); A61K 49/0093 (2013.01);
Abstract

Disclosed are Somatostatin receptor ligands comprising a peptide moiety, pharmaceutical compositions and uses thereof. Disclosed are also synthetic Somatostatin receptor ligands comprising a cyclic peptide moiety and an active agent moiety covalently bonded to the cyclic peptide moiety through a nitrogen atom of a side chain functional group of an internal residue of the cyclic peptide moiety, pharmaceutical compositions and uses thereof. Disclosed are also synthetic Somatostatin receptor ligands comprising a cyclic peptide moiety and a nanoparticle active agent moiety covalently bonded to the cyclic peptide moiety, pharmaceutical compositions and uses thereof.


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