The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2022
Filed:
Sep. 06, 2018
Applicant:
Deutsches Rheuma-forschungszentrum Berlin, Berlin, DE;
Inventors:
Koji Tokoyoda, Berlin, DE;
Akiko Takaya, Chiba, JP;
Assignee:
DEUTSCHES RHEUMA-FORSCHUNGSZENTRUM BERLIN, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/255 (2006.01); A61P 37/06 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/255 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); A61P 37/06 (2018.01);
Abstract
An isolated polypeptide includes the amino acid sequence EEAEKAKEAAEKALNEAFE or an amino acid sequence with a sequence identity of least 70%, 80%, or 90% identity to that sequence. The polypeptide is no longer than 200 or 170 amino acids. A nucleic acid encodes the polypeptide, a gene therapy vector includes the nucleic acid and genetically modified cells express the polypeptide. The polypeptide, the nucleic acid, the gene therapy vector and/or the cell can be used for the treatment of a disease associated with pathogenic long-lived plasma cells.