The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2022
Filed:
May. 21, 2018
Applicant:
The Research Foundation for the State University of New York, Buffalo, NY (US);
Inventors:
Janet R. Morrow, Williamsville, NY (US);
Eric M. Snyder, Williamsville, NY (US);
Didar Asik, Buffalo, NY (US);
Assignee:
The Research Foundation for The State University of New York, Amherst, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 15/02 (2006.01); A61K 49/08 (2006.01); A61K 49/10 (2006.01); A61K 49/12 (2006.01); A61K 49/14 (2006.01);
U.S. Cl.
CPC ...
C07F 15/025 (2013.01); A61K 49/085 (2013.01); A61K 49/106 (2013.01); A61K 49/124 (2013.01); A61K 49/128 (2013.01); A61K 49/143 (2013.01);
Abstract
Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macrocyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.