The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2022

Filed:

Jun. 23, 2020
Applicants:

Incyte Corporation, Wilmington, DE (US);

Incyte Holdings Corporation, Wilmington, DE (US);

Inventors:

Jincong Zhuo, Boothwyn, PA (US);

Meizhong Xu, Hockessin, DE (US);

Chunhong He, Boothwyn, PA (US);

Colin Zhang, Ambler, PA (US);

Ding-Quan Qian, Newark, DE (US);

David M. Burns, Philadelphia, PA (US);

Yun-Long Li, Chadds Ford, PA (US);

Brian Metcalf, Moraga, CA (US);

Wenqing Yao, Kennett Square, PA (US);

Assignees:

INCYTE HOLDINGS CORPORATION, Wilmington, DE (US);

INCYTE CORPORATION, Wilmington, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 403/06 (2006.01); A61P 35/00 (2006.01); A61K 31/53 (2006.01); A61K 31/4709 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4709 (2013.01); A61K 31/53 (2013.01); A61P 35/00 (2018.01); C07D 403/06 (2013.01);
Abstract

The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.


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