The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2022
Filed:
Jan. 19, 2018
Applicants:
The Regents of the University of California, Oakland, CA (US);
The United States Government Represented BY the Department of Veterans Affairs, Washington, DC (US);
Inventors:
Matthew Rettig, Los Angeles, CA (US);
Michael E. Jung, Los Angeles, CA (US);
D. Elshan Nakath G. Ralalage, Los Angeles, CA (US);
Jiabin An, Los Angeles, CA (US);
Assignees:
The Regents of the University of California, Oakland, CA (US);
The United States Government as Represented by the Department of Veterans Affairs, Washington, DC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 225/16 (2006.01); A61P 35/00 (2006.01); C07C 33/48 (2006.01); C07C 49/223 (2006.01); C07C 235/34 (2006.01); C07C 235/78 (2006.01); C07C 321/20 (2006.01); C07D 207/08 (2006.01); C07D 211/32 (2006.01); C07D 241/04 (2006.01); C07D 265/30 (2006.01); C07D 303/32 (2006.01); C07D 303/40 (2006.01); C07D 307/52 (2006.01); C07D 333/24 (2006.01);
U.S. Cl.
CPC ...
C07C 225/16 (2013.01); A61P 35/00 (2018.01); C07C 33/486 (2013.01); C07C 49/223 (2013.01); C07C 235/34 (2013.01); C07C 235/78 (2013.01); C07C 321/20 (2013.01); C07D 207/08 (2013.01); C07D 211/32 (2013.01); C07D 241/04 (2013.01); C07D 265/30 (2013.01); C07D 303/32 (2013.01); C07D 303/40 (2013.01); C07D 307/52 (2013.01); C07D 333/24 (2013.01);
Abstract
The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.