The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2022
Filed:
May. 21, 2013
Sanofi Pasteur Limited, Toronto, CA;
Sanofi Pasteur Biologics, Llc, Cambridge, MA (US);
Stephen Anderson, Cambridge, MA (US);
Simon Delagrave, Cambridge, MA (US);
John Hamberger, Milford, NH (US);
Qinglian Li, Aurora, CA;
Sophia Mundle, Cambridge, MA (US);
Nausheen Rahman, Toronto, CA;
SANOFI PASTEUR LIMITED, Toronto, CA;
SANOFI PASTEUR BIOLOGICS, LLC, Cambridge, MA (US);
Abstract
The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable exctpients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.