The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2022

Filed:

Nov. 21, 2019
Applicant:

Rk Pharma Solutions Llc, Piscataway, NJ (US);

Inventors:

Ravishanker Kovi, Monroe Township, NJ (US);

George Roby Thomas, Winnipeg, CA;

Nirmal Chaitanya Indravadanbhai, Gujarat, IN;

Patel Mitesh Manubhai, Gujarat, IN;

Thupalli Ajeykumar Reddy, Bangalore, IN;

Jayaraman Kannappan, Vadodara, IN;

Assignee:

RK Pharma Solutions LLC, Piscataway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/675 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/675 (2013.01); A61K 9/0019 (2013.01);
Abstract

A stable, ready-to-use injectable solution including thiotepa and one or more pharmaceutically acceptable solvents, co-solvents, and/or solubilizing agents. Formulations retain at least 90% and as high as 99% of the purity of thiotepa as measured by HPLC after storage at 25° C./60% RH for a period of 7 days. Certain formulations retain at least 99% of the purity of thiotepa as measured by HPLC after storage for at least six months at 2-8° C.


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