The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2022

Filed:

Mar. 20, 2019
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Ishan Garg, Chicago, IL (US);

Andrew C. Hoffman, Rochester, MN (US);

Geoffrey B. Johnson, Rochester, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 6/00 (2006.01); A61B 6/03 (2006.01); A61K 51/02 (2006.01);
U.S. Cl.
CPC ...
A61B 6/503 (2013.01); A61B 6/032 (2013.01); A61B 6/037 (2013.01); A61B 6/463 (2013.01); A61B 6/469 (2013.01); A61B 6/5235 (2013.01); A61K 51/025 (2013.01);
Abstract

Systems and methods for enhanced diagnosis of transthyretin-related cardiac amyloidosis in a subject are disclosed. The systems and methods may use both SPECT imaging data as well as an anatomical imaging data, such as computed tomography (CT) data, to produce a combined image. Within the combined image, the radiotracer uptake between two volumes of interests are compared, one of which may represent the left ventricle of the subject and the other may represent the blood pool retention of the subject. Combining the anatomical imaging data with SPECT data enables better anatomical delineation and helps in avoiding areas with coronary or lymph node calcifications and overlying soft tissue and bony pathologies.


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