The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
May. 11, 2018
Applicant:
Illumina Cambridge Limited, Essex, GB;
Inventors:
Roberto Rigatti, Essex, GB;
Jonathan Mark Boutell, Essex, GB;
Assignee:
Illumina Cambridge Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 30/10 (2019.01); G16B 30/00 (2019.01); C12Q 1/6869 (2018.01); B01L 7/00 (2006.01); G16C 20/20 (2019.01);
U.S. Cl.
CPC ...
G16B 30/10 (2019.02); B01L 7/52 (2013.01); C12Q 1/6869 (2013.01); G16B 30/00 (2019.02); G16C 20/20 (2019.02); C12Q 2523/125 (2013.01); C12Q 2525/117 (2013.01);
Abstract
The present disclosure provides methods and systems for determining and/or characterizing one or more haplotypes and/or phasing of haplotypes in a nucleic acid sample. In particular, the disclosure provides methods for determining a haplotype and/or phasing of haplotypes in a nucleic acid sample by incorporating synthetic polymorphisms into fragments of a nucleic acid sample and utilizing the synthetic polymorphisms in determining one or more haplotypes and/or phasing of haplotypes.