The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2022

Filed:

Sep. 01, 2017
Applicant:

Invitae Corporation, San Francisco, CA (US);

Inventors:

Hywel Bowden Jones, San Francisco, CA (US);

Andrea Lynn McEvoy, San Francisco, CA (US);

Assignee:

Invitae Corporation, San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6837 (2018.01); C12Q 1/6818 (2018.01); C12Q 1/686 (2018.01); C12Q 1/6876 (2018.01); G06T 7/11 (2017.01); G06K 9/00 (2022.01); G06K 9/46 (2006.01); G16B 40/00 (2019.01); G16B 20/00 (2019.01); G16B 30/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6837 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6876 (2013.01); G06K 9/00127 (2013.01); G06K 9/4647 (2013.01); G06T 7/11 (2017.01); G06T 2207/30072 (2013.01); G16B 20/00 (2019.02); G16B 30/00 (2019.02); G16B 40/00 (2019.02);
Abstract

A method for quantifying labels on a substrate is performed by an electronic device with one or more processors and memory. The method includes obtaining digital data corresponding to a multi-dimensional measurement over the substrate; identifying a first set of sub-portions of the digital data; and, for a respective sub-portion of the first set of sub-portions of the digital data: increasing a quantity of labels, and subtracting a reference signal distribution from the respective sub-portion to obtain subtracted sub-portion data. The method also includes obtaining subtracted digital data. The subtracted digital data includes the subtracted sub-portion data for the respective sub-portion. The method further includes identifying a second set of one or more sub-portions of the subtracted digital data; and, for a respective sub-portion of the second set of one or more sub-portions of the subtracted digital data, increasing a quantity of labels.


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