The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
Jun. 02, 2020
Applicant:
Handylab, Inc., Franklin Lakes, NJ (US);
Inventors:
Sundaresh N. Brahmasandra, Ann Arbor, MI (US);
Elizabeth Craig, Ypsilanti, MI (US);
Assignee:
HANDYLAB, INC., Franklin Lakes, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6813 (2018.01); C08G 83/00 (2006.01); C07C 233/36 (2006.01); C12N 15/10 (2006.01); C07H 1/08 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1013 (2013.01); C07C 233/36 (2013.01); C07H 1/08 (2013.01); C08G 83/003 (2013.01); C12Q 1/6813 (2013.01);
Abstract
Methods for processing polynucleotide-containing biological samples, and materials for capturing polynucleotide molecules such as RNA and/or DNA from such samples. The RNA and/or DNA is captured by polyamindoamine (PAMAM (Generation 0)) bound to a surface, such as the surface of magnetic particles. The methods and materials have high efficiency of binding RNA and of DNA, and of release, and thereby permit quantitative determinations.