The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2022

Filed:

May. 06, 2019
Applicant:

Virginia Tech Intellectual Properties, Inc., Blacksburg, VA (US);

Inventors:

Robert E. Neal, II, Richmond, VA (US);

Paulo A. Garcia, Cambridge, MA (US);

Rafael V. Davalos, Blacksburg, VA (US);

John H. Rossmeisl, Blacksburg, VA (US);

John L. Robertson, Floyd, VA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01); A61B 34/10 (2016.01); A61B 18/12 (2006.01); A61B 18/00 (2006.01); A61N 1/04 (2006.01); G16H 50/50 (2018.01);
U.S. Cl.
CPC ...
C12N 13/00 (2013.01); A61B 18/12 (2013.01); A61B 34/10 (2016.02); A61B 2018/00613 (2013.01); A61B 2034/104 (2016.02); A61B 2034/105 (2016.02); A61N 1/0412 (2013.01); G16H 50/50 (2018.01);
Abstract

The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.


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