The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2022

Filed:

Dec. 12, 2018
Applicant:

Shenzhen Targetrx, Inc., Guangdong, CN;

Inventors:

Yihan Wang, Guangdong, CN;

Huanyin Li, Guangdong, CN;

Assignee:

Shenzhen TargetRx, Inc., Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6512 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65583 (2013.01); C07F 9/6512 (2013.01);
Abstract

Disclosed are a dianilino pyrimidine compound having an inhibitory effect on protein tyrosine kinase, pharmaceutically acceptable salts, crystal forms, prodrugs, metabolites, hydrates, solvates, stereoisomers or isotopic derivatives thereof, a pharmaceutical composition containing these compounds, as well as preparation and use of these compounds. The compound has a structure as represented by formula (I), and may be used for treating ALK-mediated cancer-related symptoms, such as non-small cell lung cancer, breast cancer, nerve tumors, esophagus cancer, soft tissue cancer, lymphoma, or leukemia.


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