The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2022

Filed:

May. 29, 2020
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

J. Kent Barbay, Flourtown, PA (US);

Wenying Chai, San Diego, CA (US);

Wendy Eccles, San Diego, CA (US);

Michael D. Hack, San Diego, CA (US);

Aaron T. Herrmann, San Diego, CA (US);

William M. Jones, Jenkintown, PA (US);

Paul J. Krawczuk, Newtown, PA (US);

Kevin D. Kreutter, Arlington, MA (US);

Alec D. Lebsack, Ladera Ranch, CA (US);

Daniel J. Pippel, San Diego, CA (US);

Alexander R. Rovira, San Diego, CA (US);

Ronald L. Wolin, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.


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