The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
Aug. 17, 2017
University of Maryland, Baltimore, Baltimore, MD (US);
The Queen's University of Belfast, Belfast, GB;
Richard Thompson, Baltimore, MD (US);
Huihui Zeng, Ellicott City, MD (US);
Henryk Szmacinski, Sykesville, MD (US);
Imre Lengyel, Belfast, NF;
UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);
Abstract
The present invention provides for the use of hydroxyapatite-selective fluorescent dyes in combination with fluorescence lifetime imaging to detect any hydroxyapatite spherules or hydroxyapatite deposits in the retina tissue of a subject, including the peripheral or macula tissue, wherein the hydroxyapatite spherules or hydroxyapatite deposits initiate or support the growth of sub-RPE deposits and correlates with age-related macular degeneration and/or Alzheimer's disease.