The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
Feb. 27, 2018
Applicant:
Translate Bio, Inc., Cambridge, MA (US);
Inventors:
Anusha Dias, Cambridge, MA (US);
Jonathan Abysalh, Cambridge, MA (US);
Brian Bettencourt, Cambridge, MA (US);
Frank DeRosa, Cambridge, MA (US);
Michael Heartlein, Cambridge, MA (US);
Assignee:
Translate Bio, Inc., Lexington, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 9/127 (2006.01); C12N 15/10 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); A61P 11/00 (2006.01); A61K 9/00 (2006.01); A61K 31/7105 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6455 (2017.08); A61K 9/0075 (2013.01); A61K 9/1272 (2013.01); A61K 31/7105 (2013.01); A61K 38/1709 (2013.01); A61K 47/6911 (2017.08); A61P 11/00 (2018.01); C07K 14/4712 (2013.01); C12N 15/10 (2013.01);
Abstract
The present invention provides, among other things, improved methods and pharmaceutical compositions for treating cystic fibrosis based on codon optimized mRNA encoding a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein.