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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11253592 B1

PDFFull Text
Date of Patent:
Feb. 22, 2022

Filed:

Oct. 24, 2018

Water-soluble compounds with aggregation-induced emission characteristics

Applicant:

The Hong Kong University of Science and Technology, Hong Kong, CN;

Inventors:

Benzhong Tang, Hong Kong, CN;

Dong Wang, Hong Kong, CN;

Assignee:

THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, Hong Kong, CN;

Attorneys:

Nath, Goldberg & Meyer

Joshua B. Goldberg

Primary Examiner:

Joseph R Kosack

Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61B 90/20 (2016.01); A61N 5/06 (2006.01); C07D 409/06 (2006.01); C09K 11/07 (2006.01); G01N 21/64 (2006.01); G01N 21/76 (2006.01); G02B 21/00 (2006.01); G02B 21/16 (2006.01); C07D 215/12 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); A61B 90/20 (2016.02); A61N 5/062 (2013.01); C07D 215/12 (2013.01); C07D 409/06 (2013.01); C09K 11/07 (2013.01); G01N 21/6458 (2013.01); G01N 21/76 (2013.01); G02B 21/0076 (2013.01); G02B 21/16 (2013.01); A61N 2005/0662 (2013.01); C09K 2211/1018 (2013.01);
Abstract

The present subject matter relates to water-soluble, fluorescent compounds that have aggregation-induced emission (AIE) characteristics and exhibit near infrared (NIR) absorption. The compounds can be utilized as plasma-membrane specific bio-probes in cell imaging through a wash-free and fast staining procedure. In addition, the compounds can efficiently generate reactive oxygen species (ROS) in vivo when irradiated with visible light. As such, the compounds can be effective in killing cancer cells through image-guided, photodynamic therapy (PDT) processes.

Find Patent Forward Citations

Tang, Benzhong. (2022). Water-soluble compounds with aggregation-induced emission characteristics (U.S. Patent No. 11253592). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11253592

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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