The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
Oct. 12, 2017
Applicant:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Inventors:
Howard Weiner, Brookline, MA (US);
Francisco J. Quintana, Jamaica Plain, MA (US);
Assignee:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/135 (2006.01); A61K 31/137 (2006.01); A61K 39/395 (2006.01); A61K 31/405 (2006.01); C12N 5/0783 (2010.01); G01N 33/50 (2006.01); A61K 31/357 (2006.01); A61K 31/4045 (2006.01); A61K 31/407 (2006.01); A61K 31/427 (2006.01); A61K 35/17 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/135 (2013.01); A61K 31/137 (2013.01); A61K 31/357 (2013.01); A61K 31/405 (2013.01); A61K 31/407 (2013.01); A61K 31/4045 (2013.01); A61K 31/427 (2013.01); A61K 35/17 (2013.01); C12N 5/0636 (2013.01); G01N 33/5088 (2013.01); A61K 2035/122 (2013.01); C12N 2501/38 (2013.01); C12N 2501/60 (2013.01);
Abstract
Methods for identifying compounds that modulate the generation of regulatory T cells (Treg) in vivo and in vitro, i.e., compounds that act on the transcription factors that increase or decrease expression of Foxp3.