The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 22, 2022

Filed:

Mar. 11, 2019
Applicant:

Napa Medical Research Foundation, Napa, CA (US);

Inventors:

Ryan Dregalla, Lyons, CO (US);

Marko Bodor, Napa, CA (US);

Yvette Uribe, Napa, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/19 (2015.01); A61K 35/28 (2015.01); C12N 5/0735 (2010.01); C12N 5/078 (2010.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61K 35/19 (2013.01); A61K 35/28 (2013.01); C12N 5/0606 (2013.01); C12N 5/0608 (2013.01); C12N 5/0644 (2013.01); C12N 2509/10 (2013.01); C12N 2527/00 (2013.01);
Abstract

A method of producing the constituents of a therapeutic product from mammalian cells is described herein. Cells are isolated from a mammalian source. The cells are exposed to supercritical carbon dioxide (SCCO) for 1 to 30 minutes, where the SCCOis maintained at a pressure of 1071 pounds per square inch (PSI) and a temperature of 31.1 to 45 degrees Celsius during the exposure. The exposure dissociates the cellular membranes of the cells to release intramembrane components therein to produce constituents of the therapeutic product. The mammalian cells may include at least one of platelets, stem cells, germ cells, and somatic cells. The methods described herein are particularly advantageous for releasing and capturing therapeutic intramembrane components from platelets and alpha-granules.


Find Patent Forward Citations

Dregalla, Ryan. (2022). Method of producing the constituents of a therapeutic product from mammalian cells (U.S. Patent No. 11253548). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11253548

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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