The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
Sep. 26, 2016
Applicant:
Ludwig Institute for Cancer Research Ltd, Zurich, CH;
Inventors:
Timothy Gahman, Encinitas, CA (US);
Andrew Shiau, San Diego, CA (US);
Richard Kolodner, La Jolla, CA (US);
Assignee:
Ludwig Institute for Cancer Research Ltd, Zurich, CH;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/517 (2006.01); A61K 45/06 (2006.01); C07D 239/96 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01); C07D 239/96 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01);
Abstract
Described inter alia are compounds according to formula (I): or a pharmaceutically acceptable salt thereof, and uses in methods for the modulation of flap endonuclease 1 (FEN1), Xeroderma Pigmentosum Complementation Group G protein (XPG), Exonuclease 1 (EXO1) and/or GEN1.