The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
Nov. 21, 2019
Applicant:
Baylor College of Medicine, Houston, TX (US);
Inventors:
Bert W. O'Malley, Houston, TX (US);
David Michael Lonard, Pearland, TX (US);
Jin Wang, Sugar Land, TX (US);
Jianming Xu, Bellaire, TX (US);
Jianwei Chen, Houston, TX (US);
Assignee:
BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); A61K 31/506 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); A61K 31/4184 (2006.01); A61K 31/426 (2006.01); A61K 31/4402 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/4184 (2013.01); A61K 31/426 (2013.01); A61K 31/4402 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01);
Abstract
Small molecule regulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing SRC-related diseases. The SRC-related diseases can include cancer, metabolic disorders, human immunodeficiency virus, neurodegenerative disorders, and/or inflammatory diseases. Also provided are methods for regulating SRC family proteins in a cell.