The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 22, 2022
Filed:
May. 04, 2018
Applicant:
Alkermes Pharma Ireland Limited, Dublin, IE;
Inventors:
Niels P. Ryde, Malvern, PA (US);
Peter Snyder, King of Prussia, PA (US);
Wei Liu, Exton, PA (US);
David M. Slifer, Downingtown, PA (US);
Assignee:
Alkermes Pharma Ireland Limited, Dublin, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 31/5415 (2006.01); A61K 9/10 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61K 47/28 (2006.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1623 (2013.01); A61K 9/0019 (2013.01); A61K 9/10 (2013.01); A61K 9/145 (2013.01); A61K 9/146 (2013.01); A61K 9/1617 (2013.01); A61K 9/1635 (2013.01); A61K 9/1688 (2013.01); A61K 31/5415 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61K 47/28 (2013.01); A61K 47/32 (2013.01);
Abstract
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising a nanoparticulate active agent, at least one surface stabilizer and a flake-like aggregation reducing agent, such as a buffer and a sugar. The nanoparticulate active agent compositions comprise particles of the active agent having an effective average particle size of less than about 2000 nm.