The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Mar. 27, 2018
Applicant:
Janssen Vaccines & Prevention B.v., Leiden, NL;
Inventors:
Rosa Crespo Rodriguez, The Hague, NL;
Constantin Adrian Apetri, Noordwijkerhout, NL;
Assignee:
Janssen Vaccines & Prevention B.V., Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); C07K 14/4711 (2013.01);
Abstract
The present invention provides a method for the in vitro formation and/or detection of paired helical filaments (PHF) of Tau protein, comprising incubating a mixture comprising a Tau protein preparation and a polyanionic co-factor for a pre-determined period of time under conditions that promote the formation of PHFs.